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Aortic Valve Disease

Aortic valve disease is a type of heart valve disease. In aortic valve disease, the valve between the lower left heart chamber (left ventricle) and the main artery to the body (aorta) doesn't work properly.

The aortic valve helps keep blood flowing in the correct direction through the heart. A damaged or diseased aortic valve can affect blood flow to the rest of the heart and body.

Aortic valve disease includes:

  • Aortic valve stenosis. The flaps (cusps) of the aortic valve become thick and stiff, or they fuse together. These problems cause the valve opening to become narrow. The narrowed valve reduces or blocks blood flow from the heart to the rest of the body.
  • Aortic valve regurgitation. The aortic valve doesn't close properly, causing blood to flow backward into the left lower heart chamber (ventricle).

Aortic valve disease may be present at birth (congenital heart disease), or it may occur later in life due to other health conditions.

Treatment for aortic valve disease depends on the type and severity of disease. Some people may need surgery to repair or replace the aortic valve.


Some people with aortic valve disease may not notice symptoms for many years. Signs and symptoms of aortic valve disease may include:

  • Whooshing or swishing heart sound (heart murmur)
  • Chest pain or tightness
  • Dizziness
  • Fainting
  • Fatigue after activity or having less ability to be active
  • Irregular heartbeat
  • Shortness of breath, particularly during vigorous activity or when lying down
  • Not eating enough (mainly in children with aortic valve stenosis)
  • Not gaining enough weight (mainly in children with aortic valve stenosis)

Risk factors

Many things can raise the risk of aortic valve disease, including:

  • Older age. Calcium deposits can build up on the aortic valve as people age, causing the aortic valve to stiffen and become narrow.
  • Heart valve problems present at birth (congenital heart defects). Some people are born with a missing, extra or fused valve flap (cusp), increasing the risk of aortic valve regurgitation.
  • Rheumatic fever. This complication of strep throat can cause aortic stenosis, a type of valve disease. If you have heart valve disease due to rheumatic fever, it's called rheumatic heart disease. If not, it's called nonrheumatic heart disease.
  • Inflammation of the lining of the heart's chambers and valves (endocarditis). This life-threatening condition is usually caused by infection. It can damage the aortic valve.
  • History of radiation therapy to the chest. Some types of cancer are treated with radiation therapy. Symptoms of heart valve disease may not be noticed until many years after radiation therapy is received.
  • Other health conditions. Chronic kidney disease, lupus and Marfan syndrome, a connective tissue disease, can increase the risk of aortic stenosis or regurgitation.
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